Abstract Background The three-dimensional genome organization is critical for gene regulation and can malfunction in diseases like cancer.As a key regulator of genome organization, CCCTC-binding factor (CTCF) has been characterized as a DNA-binding protein with important functions in maintaining the topological structure of chromatin and inducing D
The researchers aimed at analyzing the meaning of humor in newspaper comic strips within a variety of incongruous combinations of multimodal rhetoric.The current research focused on how humor was produced via verbal medium only, via both verbal and visual media, as well as via visual only.The source of data was 74 political comic strips featured in
The incorporation of sophisticated capabilities within microfluidic devices often requires the assembly of different layers in a correct arrangement.For example, when it is desired to include electrodes inside microfluidic channels or to create 3D microfluidic structures.However, the alignment between different substrates at the microscale requires
Abstract Orally administered nanocarriers play an important role in improving druggability, promoting intestinal absorption, and enhancing therapeutic applications for the treatment of local and systemic diseases.However, the delivering efficiency and cell response in mucosa to orally administered nanocarriers is affected by the physiological envir
With the improvements in surgical technique, the indications for liver transplantation(LT) are being expanded to more complex and severe patients, who not only have liver function in the terminal stage, but also extrahepatic organs involve of varying degrees dysfunction.It was redken shades eq 07m driftwood demonstrated that the strategy of extrahe